Guard Column starter set, Diamond Hydride, complete with 5 each 4.0 mm ID x 10 mm long cartridges packed with 4 um, 100 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 PK.
Additional Info:
The 70000‑PG4 Diamond Hydride Guard Column Starter Set is designed to protect analytical HPLC columns from particulate contamination, matrix interferences, and strongly retained compounds that can degrade chromatographic performance and shorten column lifespan.
This complete starter set provides everything required to implement a correct guard‑column strategy for Cogent TYPE‑C™ Diamond Hydride analytical methods using larger‑diameter analytical columns—without altering retention mechanisms or chromatographic selectivity.
Guard Column Use Case: Protecting Larger‑ID Analytical Columns
Guard columns are installed upstream of the analytical column and act as a sacrificial bed that captures contaminants before they reach the analytical stationary phase.
Critical Requirement: To maintain chromatographic integrity, the stationary phase in the guard cartridge must match the stationary phase of the analytical column.
The Diamond Hydride guard cartridges included in this set ensure:
No change in retention mechanism
No loss of resolution
No selectivity shift
No peak distortion
Using a guard cartridge packed with a different stationary phase can compromise chromatographic performance and method validity.
What’s Included in This Starter Set
This kit includes all components required to begin using Cogent TYPE‑C™ guard columns with larger‑ID analytical columns:
Stainless Steel Guard Cartridge Holder
Precision‑machined stainless steel construction
Compatible with all Cogent TYPE‑C™ guard cartridges
Designed for stable, leak‑free operation under analytical HPLC conditions
Five Diamond Hydride Guard Cartridges
4.0 mm ID × 10 mm length
Packed with Diamond Hydride stationary phase, 4 µm, 100 Å
Provides sufficient protection for the typical lifetime of an analytical column under average usage conditions
Each cartridge is shipped in an individual resealable Delrin case to prevent drying or handling damage
Analytical Column Compatibility
This guard column system is designed for use with:
3.0 mm ID analytical columns
4.0 mm ID analytical columns
4.6 mm ID analytical columns
It is intended for use with Cogent TYPE‑C™ Diamond Hydride analytical columns and similar applications where retention‑mechanism consistency is required.
Guard Column Installation Best Practices
To preserve chromatographic efficiency, the guard column holder should be installed as close to the analytical column inlet as physically possible.
Minimizing distance between the guard and analytical column reduces extra‑column (dead) volume, which can otherwise lead to:
Band broadening
Reduced efficiency
Loss of resolution
Peak tailing or distortion
When installed immediately upstream of the analytical column and paired with matching Diamond Hydride stationary phase, the guard system protects the analytical column without degrading separation performance.
Purpose‑Built for Method Protection & Column Longevity
The 70000‑PG4 guard column starter set is commonly used in:
Routine analytical laboratories
Method development environments
HILIC and LC‑MS workflows
Regulated applications requiring long‑term method consistency
Proper guard column use can significantly extend analytical column lifetime, reduce downtime, and improve reproducibility across multiple analytical runs.
System Requirements
Compatible with standard analytical HPLC systems
Installed between injector and analytical column
No method changes required when stationary phases are properly matched